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July CKD Insider Newsletter- Learn About The Latest Dialysis Innovations

Welcome to the Chronic Kidney Disease Newsletter July edition. If you are person with chronic kidney disease (CKD) on dialysis or helping care for someone who is, this newsletter was created for you! The content is meant to keep you and/or a family member up to date on the latest information to help you manage your health now or in the near future in consultation with your physician.


In this month’s CKD Insider : Kidney Week Reimagined, Fun Tip of the Day, Research in the News, and Kidney X Dialysis Redesign winner summaries.                               

Kidney Week Reimagined

  • For the nephrologists and researchers in the group, the American Society of Nephrology (ASN) is holding their annual meeting virtually this year. See key information below.

  • Dates: Early Programs October 19-21st, Main meeting from October 22- 25th.

  • They are still taking late-breaking clinical trial submissions. The Submission deadline is Wednesday, September 2nd at 2pm EST. Learn more here.

Fun Tip of the Day!

Ready to venture out? Take a trip to the beach! Finding a beach that allows you to social distance might seem like a challenge, but also consider the time of day you go. Some beaches are crowded during the day, but start to clear out around dinner time as people leave, still leaving you plenty of time to enjoy the space while social distancing. Find your perfect time & spot! _____________________________________________________________________________________________________

Research in the News Kidney transplantation between people with HIV is safe


What’s the latest: A multicenter study looked at the safety and risk of an HIV+ donor versus an HIV – donor providing a kidney to a person who is HIV+ and found there were no deaths or differences in one-year graft survival, one-year mean estimated glomerular filtration rate, HIV breakthrough, infectious hospitalizations or opportunistic infections. All of which is a good sign! One year rejection was higher for HIV+ donor recipients, but not significantly, and is being investigated further. Why it’s important: If you are a person living with HIV (HIV+) and are interested in kidney transplantation, this study provides you and your doctors with some positive news in relation to your options and the outcomes seen.

References:

  1. A Prospective Multicenter Pilot Study of HIV‐Positive Deceased Donor to HIV‐Positive Recipient Kidney Transplantation: HOPE in Action. American Journal of Transplantation. July 23, 2020: https://doi.org/10.1111/ajt.16205

  2. Contemporary issues and new challenges in chronic kidney disease amongst people living with HIV. AIDS Research and Therapy. March 16, 2020


Innovative Dialysis Inventions

Learn what the 6 Kidney X Dialysis Redesign Phase 2 Winners are up to!

The American Society of Nephrology and the US Department of Health and Human Services announced the winners of KidneyX Redesign Dialysis Phase 2 on July 23rd. All of these ideas have the potential to make an impact in you or a loved ones day to day life! Read below for brief summaries and read more details here.

NitriCap What it is: Nitric Oxide-Eluting, Disposable Hemodialysis Catheter Cap to Prevent Infection and Thrombosis. This small cap is placed on the catheter, the Nitric Oxide that is released released decreases biofilm formation, which allow bacteria to hide from immune system. Why it’s important: If you are ever in need of a catheter for dialysis, you will be informed of the dangers of infection associated with catheter placement and usage. This cap has the potential to decrease the infection rate and give you peace of mind. Early animal studies are very promising and have shown a 100,000 fold reduction in biofilm formation versus an FDA approved infection prevention device for dialysis catheters. Status: Patent pending. Currently in 9 month verification phase, FDA 510K submission will follow. Timeline: Plan to bring to dialysis units in 2022. Hear from inventors here. VenoStent What it is: SelfWrap(TM) - A bioresorbable wrap that improves fistula maturation. Why it’s important: Quicker fistula maturation and usability can help doctors predict if they will need to provide you with a catheter beforehand and reduce physical complications. Status: Human trials outside the US planned. Hear from inventors here. Relavo What it is: PeritoneX -  an intermediate connection device that internally disinfects connected peritoneal dialysis tubes to prevent contamination. Why it’s important: If you are a peritoneal dialyzer, this can alleviate the concern and stress about infection and give you an additional layer of peace of mind. Status: Currently doing human factors trial, ending 2021 and starting user study with American association kidney foundation in coming months. Plans are for clinical trial in 2022. Hear from inventors here. iHemo What it is: Surgically implanted hemodialysis cartridge placed in the abdomen that connects externally to a portable dialysate recirculation pump. Why it’s important: This would simplify the hemodialysis procedure, making it easier for in home hemodialysis and during your travels, as no fistula or graft would be needed and the external pump is portable. Status: Proof of concept work has been completed. Next plans are to work on safety of cartridge in humans. Hear from inventors here. Vasobio What it is: VasoCoat™ - a technology to coat vascular grafts used for hemodialysis with endothelial progenitor cells to attract endothelial cells and allow improved graft acceptance. Why it’s important: This technology could help your vascular graft stay healthy longer and reduce the potential follow up procedures needed leading to improved quality of life. Status: Prototype is in testing phase in animal models. Hear from inventors here. Center for Dialysis Innovation (CDI) What it is: Pro-regenerative vascular arteriovenous (AV) graft for hemodialysis that heals in place like a natural artery. Why it’s important: If you are in need of an AV graft, this fabricated graft has the potential to improve your experience and minimize challenges associated with graft failure. Status: Technology under development. Preliminary studies in animals were successful. Patent approved. Hear from inventors here.

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